Systemic Lupus Erythematosus: Clinical AspectsAbout This Hardback Systemic lupus erythematosus (SLE) is an autoimmune disease of the body in which the immune system attacks healthy tissue. It is known as the great imitator as it mimics the symptoms of other illnesses. Some common complaints are joint pains, fever, malaise, fatigue and muscle pains. The presentation of the disease can be different in males and females. Women tend to have more relapses, arthritis, a low white blood cell count,