Will Vaping Set Off Hotel Smoke Alarms? Can Hotel Smoke Detectors Detect Vape Can Hotel Rooms Detect Vape Smoke Can You Vape in a Hotel Room? Read This Guide Can Vapor Set Off a Smoke Alarm? What to Know Dr.Dabber A pair of hackers found that a vape detector often found in high school bathrooms contained microphonesand security weaknesses that could allow someone to turn it into a secret listening device.