Condoms protect against unplanned pregnancy and most sexually transmitted infections, including HIV, gonorrhoea, chlamydia, and syphilis. Use only water or silicone based lubricant with a condom during vaginal and particularly anal sex What's the difference between regular condoms and condoms with spermicide? When trying to conceive, choosing the right lubricant matters. Some common products like oil based lubricants, petroleum jelly, saliva, and regular lubricants may harm sperm and reduce fertility chances. Instead, opt for fertility friendly, Study finds PFAS in condoms and lube, prompting concerns about sperm and overall health